Paroxetine hydrochloride
USP/1500218 - United States Pharmacopeia (USP) Reference Standard
Synonym: Paroxetine hydrochloride hemihydrate; (3S-
CAS Number: 110429-35-1
Empirical Formula (Hill Notation): C19H20FNO3 · HCl · .5 H2O
Molecular Weight: 374.83
MDL Number: MFCD03658863
Linear Formula: C19H20FNO3 · HCl · .5 H2O
Product Type: Chemical
| API family | paroxetine |
| application(s) | pharmaceutical (small molecule) |
| format | neat |
| grade | pharmaceutical primary standard |
| InChI | 1S/C19H20FNO3.ClH.H2O/c20 |
| InChI key | QRQSGFFISBKLMZ-YHOFXEKLSA |
| manufacturer/tradename | USP |
| SMILES string | O.Cl[H].Fc1ccc(cc1)[C@@H] |
| Analysis Note: | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
| Application: | Paroxetine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. |
| Biochem/physiol Actions: | Paroxetine hydrochloride hemihydrate is one of the most potent and selective of the selective serotonin reuptake inhibitors (SSRI); antidepressant |
| Biochem/physiol Actions: | Selective serotonin reuptake inhibitor; antidepressant |
| General description: | Paroxetine hydrochloride is a phenylpiperidine derivative which is selective serotonin reuptake inhibitor. The protein binding ability is high. It has 2 forms, non-hygroscopic hemihydrate and hygroscopic anhydrate. This drug is seen useful in treating premature ejaculation in men. |
| General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia ![]() |
| Other Notes: | Sales restrictions may apply. |
| Symbol | ![]() GHS07,GHS09 |
| Signal word | Warning |
| Hazard statements | H302 - H411 |
| Precautionary statements | P273 - P301 + P312 + P330 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 41116107 |



