Phenacetin Melting Point Standard
USP/1514008 - United States Pharmacopeia (USP) Reference Standard
Synonym: Phenacetin; 1-Acetyl-p-phenetidin; 4′-Ethoxyacetanilide; N-
CAS Number: 62-44-2
Empirical Formula (Hill Notation): C10H13NO2
Molecular Weight: 179.22
EC Number: 200-533-0
MDL Number: MFCD00009094
Linear Formula: CH3CONHC6H4OC2H5
Product Type: Chemical
| API family | phenacetin |
| application(s) | pharmaceutical (small molecule) |
| format | neat |
| grade | pharmaceutical primary standard |
| InChI | 1S/C10H13NO2/c1-3-13-10-6 |
| InChI key | CPJSUEIXXCENMM-UHFFFAOYSA |
| manufacturer/tradename | USP |
| mp | 133-136 °C (lit.) |
| SMILES string | CCOc1ccc(NC(C)=O)cc1 |
| Analysis Note: | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
| Application: | Phenacetin Melting Point Standard USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. |
| Biochem/physiol Actions: | Substrate of CYP1A2 and CYP2D6. |
| General description: | Phenacetin Melting Point Standard (Phenacetin) is a lipid-soluble drug with moderate solubility with aqueous solvents. Its oral absorption is based on formulation factors like particle size. Its major metabolic route is O-dealkylation to paracetamol and its minor pathways are deacetylation and hydroxylation to form pphenetidine, 2-hydroxyphenetidine, 2- and 3-hydroxyphenacetin and N-hydroxyphenacetin. |
| Other Notes: | Sales restrictions may apply. |
| Symbol |   GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H302 - H350 |
| Precautionary statements | P202 - P264 - P270 - P280 - P301 + P312 - P308 + P313 |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 133-136 °C (lit.) |
| UNSPSC | 41116107 |