Physostigmine salicylate
USP/1537003 - United States Pharmacopeia (USP) Reference Standard
Synonym: Eserine salicylate salt; Physostigmine salicylate salt
CAS Number: 57-64-7
Empirical Formula (Hill Notation): C15H21N3O2 · C7H6O3
Molecular Weight: 413.47
MDL Number: MFCD00135659
Linear Formula: C15H21N3O2 · C7H6O3
Product Type: Chemical
| API family | physostigmine |
| application(s) | pharmaceutical (small molecule) |
| format | neat |
| grade | pharmaceutical primary standard |
| InChI | 1S/C15H21N3O2.C7H6O3/c1-1 |
| InChI key | HZOTZTANVBDFOF-PBCQUBLHSA |
| manufacturer/tradename | USP |
| mp | 181-183 °C |
| SMILES string | OC(=O)c1ccccc1O.CNC(=O)Oc |
| Analysis Note: | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
| Application: | Physostigmine salicylate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as: • Physostigmine Salicylate Injection |
| Biochem/physiol Actions: | Acetylcholinesterase inhibitor that crosses the blood-brain barrier and forms a carbamylated enzyme complex with acetyl cholinesterase that degrades slowly. |
| General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia ![]() |
| Other Notes: | Sales restrictions may apply. |
| Symbol | GHS06 |
| Signal word | Danger |
| Hazard statements | H300 + H330 |
| Precautionary statements | P260 - P301 + P330 + P331 + P310 - P304 + P340 + P310 - P403 + P233 |
| RIDADR | UN1544 - class 6.1 - PG 1 - RQ - Alkaloid salts, solid, n.o.s., |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 181-183 °C |
| UNSPSC | 41116107 |


