Polymyxin B sulfate
USP/1547007 - United States Pharmacopeia (USP) Reference Standard
CAS Number: 1405-20-5
MDL Number: MFCD30489731
Product Type: Chemical
| API family | polymyxin |
| application(s) | USP Biologics pharmaceutical (small molecule) |
| form | powder |
| format | neat |
| grade | pharmaceutical primary standard |
| InChI | 1S/C48H82N16O13.H2O4S/c1- |
| InChI key | HNDFYNOVSOOGDU-UHFFFAOYSA |
| manufacturer/tradename | USP |
| SMILES string | [S](=O)(=O)(O)O.N1CCC(C(= |
| storage temp. | 2-8°C |
| Analysis Note: | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
| Application: | Polymyxin B sulfate USP Reference standard suitable for use in specified USP compendial tests and assays. Also, for use with USP monographs such as: • Bacitracin and Polymyxin B Sulfate Topical Aerosol® • Oxytetracycline Hydrochloride and Polymyxin B Sulfate Ointment • Polymyxin B Sulfate and Trimethoprim Ophthalmic Solution • Bacitracin Zinc and Polymyxin B Sulfate Ointment • Polymyxin B Sulfate and Hydrocortisone Otic Solution • Chloramphenicol and Polymyxin B Sulfate Ophthalmic Ointment • Oxytetracycline Hydrochloride and Polymyxin B Sulfate Ophthalmic Ointment |
| General description: | Polymyxin B sulfate is a mixture of closely related cyclic polypeptides produced by Bacillus polymyxa. It disrupts the integrity of Gram-negative bacterial membranes by binding to lipopolysaccharides. The USP reference standard is used in microbiological potency assays and system suitability testing. The USP biologics antibiotics category includes a wide range of antimicrobial agents that are essential in treating bacterial infections. These antibiotics are derived from various natural sources or synthesized to combat specific pathogens effectively. The USP provides comprehensive standards, reference materials, and analytical procedures to ensure the identity, quality, purity, and consistency of antibiotic therapeutics throughout their lifecycle. The United States Pharmacopeia (USP) provides quality standards for biologics to ensure their safety, efficacy, and quality throughout the manufacturing process. These standards assist manufacturers in adhering to regulatory requirements and help safeguard public health by reducing risks associated with biologics. |
| Legal Information: | Aerosol is a registered trademark of Cytec Technology Corp. |
| Other Notes: | Sales restrictions may apply. |
| Other Notes: | This product is part of USP Biologics Program. |
| Other Notes: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia ![]() |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 41116107 |

