Streptomycin sulfate
USP/1623003 - United States Pharmacopeia (USP) Reference Standard
Synonym: Streptomycin sulfate salt
CAS Number: 3810-74-0
Empirical Formula (Hill Notation): C21H39N7O12 · 1.5H2O4S
Molecular Weight: 728.69
MDL Number: MFCD00037023
Linear Formula: C21H39N7O12 · 1.5 H2SO4
Product Type: Chemical
API family | streptomycin |
application(s) | pharmaceutical (small molecule) |
format | neat |
grade | pharmaceutical primary standard |
InChI | 1S/2C21H39N7O12.3H2O4S/c2 |
InChI key | QTENRWWVYAAPBI-YZTFXSNBSA |
manufacturer/tradename | USP |
SMILES string | OS(O)(=O)=O.OS(O)(=O)=O.O |
storage temp. | −20°C |
Analysis Note: | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
Application: | Streptomycin sulfate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. |
Biochem/physiol Actions: | Mode of Action: Streptomycin acts by inhibiting prokaryote protein synthesis by binding to the S12 protein of the 30S ribosomal subunit, thus preventing the transition from imitation complex to chain-elongating ribosome. This causes miscoding or inhibits initiation. Mode of Resistance: A mutation in rpsL, a gene for S12 ribosomal protein, prevents binding of streptomycin to the ribosome. An aminoglycoside phosphotransferase also inactivates streptomycin. Antimicrobial spectrum: Streptomycin acts against gram-negative and gram-positive bacteria. |
General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia . |
Other Notes: | Sales restrictions may apply. |
Symbol | GHS07,GHS08 |
Signal word | Warning |
Hazard statements | H302 - H361fd |
Precautionary statements | P201 - P202 - P264 - P270 - P301 + P312 - P308 + P313 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | −20°C |
UNSPSC | 41116107 |