Tacrolimus
USP/1642802 - United States Pharmacopeia (USP) Reference Standard
Synonym: FK-506 monohydrate; Tacrolimus
CAS Number: 109581-93-3
Empirical Formula (Hill Notation): C44H69NO12 · H2O
Molecular Weight: 822.03
MDL Number: MFCD11045918
Linear Formula: C44H69NO12 · H2O
Product Type: Chemical
application(s) | pharmaceutical (small molecule) |
format | neat |
grade | pharmaceutical primary standard |
InChI | 1S/C44H69NO12.H2O/c1-10-1 |
InChI key | NWJQLQGQZSIBAF-MLAUYUEBSA |
manufacturer/tradename | USP |
SMILES string | O.CO[C@@H]1C[C@@H](CC[C@H |
Analysis Note: | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
Biochem/physiol Actions: | FK-506 is a potent immunosuppressant, neuroprotective and neuroregenerative, and in vitro T cell proliferation blocker. FK-506 disrupts calcineurin-mediated signal transduction in T lymphocytes and interacts with its FK-506-binding protein-12 (FKBP12). |
General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia . |
Other Notes: | Sales restrictions may apply. |
Other Notes: | USP issued SDS can be found here . |
Symbol | GHS06 |
Signal word | Danger |
Hazard statements | H301 |
Precautionary statements | P301 + P330 + P331 + P310 |
RIDADR | UN 2811 6.1 / PGIII |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
UNSPSC | 41116107 |