Thioguanine
USP/1660000 - United States Pharmacopeia (USP) Reference Standard
Synonym: 6-Thioguanine; 2-
CAS Number: 154-42-7
Empirical Formula (Hill Notation): C5H5N5S
Molecular Weight: 167.19
MDL Number: MFCD00233553
Linear Formula: C5H5N5S
Product Type: Chemical
| API family | thioguanine, tioguanine |
| application(s) | pharmaceutical (small molecule) |
| format | neat |
| grade | pharmaceutical primary standard |
| InChI | 1S/C5H5N5S/c6-5-9-3-2(4(1 |
| InChI key | WYWHKKSPHMUBEB-UHFFFAOYSA |
| manufacturer/tradename | USP |
| mp | ≥300 °C (lit.) |
| SMILES string | NC1=Nc2nc[nH]c2C(=S)N1 |
| Analysis Note: | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
| Application: | Thioguanine USP Reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monograph such as Thioguanine Tablets |
| Biochem/physiol Actions: | Ribosylated and phosphorylated by the same pathway as natural purine bases; as the nucleotide, inhibits a variety of cellular processes involved in nucleic acid synthesis. Has a long history as an effective treatment of leukemia. |
| General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia   . |
| Other Notes: | Sales restrictions may apply. |
| Symbol |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P301 + P330 + P331 + P310 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | ≥300 °C (lit.) |
| UNSPSC | 41116107 |