Tobramycin

USP/1667508 - United States Pharmacopeia (USP) Reference Standard

Synonym: Nebramycin Factor 6; O-[3-Amino-3-deoxy-α-D-glucopyranosyl-(1→6)]-O-[2,6-diamino-2,3,6-trideoxy-α-D-ribohexopyranosyl-(1→4)]-2-deoxy-D-streptamine

CAS Number: 32986-56-4
Empirical Formula (Hill Notation): C₁₈H₃₇N₅O₉
Molecular Weight: 467.51
MDL Number: MFCD00077885
Linear Formula: C₁₈H₃₇N₅O₉
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-1667508-350MG	350 mg	$474.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

API family	tobramycin
application(s)	pharmaceutical (small molecule)
format	neat
grade	pharmaceutical primary standard
InChI	1S/C18H37N5O9/c19-3-9-8(25)2-7(22)17(29-9)31-15-5(20)1-6(21)16(14(15)28)32-18-13(27)11(23)12(26)10(4-24)30-18/h5-18,24-28H,1-4,19-23H2/t5-,6+,7+,8-,9+,10+,11+,12+,13+,14-,15+,16-,17+,18+/m0/s1
InChI key	NLVFBUXFDBBNBW-SNGYORCQSA-N
manufacturer/tradename	USP
SMILES string	NC[C@H]1O[C@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@@H](N)[C@H]3O)[C@H]2O)[C@H](N)C[C@@H]1O
storage temp.	2-8°C

Analysis Note:	These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Application:	It is intended to be used as a USP reference standard in specified quality tests and assays.(1) Also used to prepare the standard solution for identification and assay of tobramycin and its different dosage forms using thin-layer chromatography (TLC) and liquid chromatography (LC) combined with UV detection at 365 nm respectively, as prescribed in the United States Pharmacopeia (USP) for the following monographs:• Tobramycin • Tobramycin for Injection • Tobramycin Ophthalmic Ointment • Tobramycin Ophthalmic Solution • Tobramycin Injection • Tobramycin Sulfate • Tobramycin and Dexamethasone Ophthalmic Suspension • Tobramycin Inhalation Solution • Tobramycin and Fluorometholone Acetate Ophthalmic Suspension • Tobramycin and Dexamethasone Ophthalmic Ointment
Biochem/physiol Actions:	Tobramycin is an aminoglycoside. Mode of Action: Binds to 70S ribosomal subunit; inhibits translocation; elicits miscoding. Spectrum of Activity: Gram negative bacteria. Not effective against Enterococci.
General description:	This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia .
Other Notes:	Sales restrictions may apply.

Symbol	GHS08,GHS08
Signal word	Warning-Warning
Hazard statements	H361f - H361f
Precautionary statements	P201 - P202 - P280 - P201 - P202 - P280 - P308 + P313 - P308 + P313 - P405 - P405 - P501 - P501
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3

Storage Temp.	2-8°C
UNSPSC	41116107

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