Tretinoin
USP/1674004 - United States Pharmacopeia (USP) Reference Standard
Synonym: Retinoic acid; ATRA; Tretinoin; Vitamin A acid; all-trans-Retinoic acid
CAS Number: 302-79-4
Empirical Formula (Hill Notation): C20H28O2
Molecular Weight: 300.44
MDL Number: MFCD00001551
Linear Formula: C20H28O2
Product Type: Chemical
application(s) | pharmaceutical (small molecule) |
format | neat |
grade | pharmaceutical primary standard |
InChI | 1S/C20H28O2/c1-15(8-6-9-1 |
InChI key | SHGAZHPCJJPHSC-YCNIQYBTSA |
manufacturer/tradename | USP |
mp | 180-181 °C (lit.) |
SMILES string | CC1=C(C=CC(C)=CC=CC(C |
Analysis Note: | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
Biochem/physiol Actions: | all−trans−Retinoic acid (ATRA) is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). The bound RAR and RXR act as transcription factors that regulate the growth and differentiation of both normal and malignant cells. Cytochromes P450 (CYPs) catalyze the 4-hydroxylation of ATRA. Retinoic acid primes embryonic stem cells to become neurons. |
General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia . |
Other Notes: | Sales restrictions may apply. |
Other Notes: | USP issued SDS can be found here . |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H302 - H315 |
Precautionary statements | P264 - P270 - P280 - P301 + P312 - P302 + P352 - P332 + P313 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 2 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
mp | 180-181 °C (lit.) |
UNSPSC | 41116107 |