Tretinoin

USP/1674004 - United States Pharmacopeia (USP) Reference Standard

Synonym: Retinoic acid; ATRA; Tretinoin; Vitamin A acid; all-trans-Retinoic acid

CAS Number: 302-79-4
Empirical Formula (Hill Notation): C₂₀H₂₈O₂
Molecular Weight: 300.44
MDL Number: MFCD00001551
Linear Formula: C₂₀H₂₈O₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-1674004-5X30MG	30 mg	$436.00 5/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

API family	tretinoin
application(s)	pharmaceutical (small molecule)
format	neat
grade	pharmaceutical primary standard
InChI	1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+
InChI key	SHGAZHPCJJPHSC-YCNIQYBTSA-N
manufacturer/tradename	USP
mp	180-181 °C (lit.)
SMILES string	CC1=C(C=CC(C)=CC=CC(C)=CC(O)=O)C(C)(C)CCC1

Analysis Note:	These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.
Application:	Tretinoin USP reference standard for use in specified quality tests and assays. Also used to prepare standard, standard stock, system suitability and system suitability stock solutions for assay, identification and impurity analysis according to given below monographs of the United States Pharmacopeia (USP): • Tretinoin • Isotretinoin • Acitretin • Tretinoin Topical Solution
Biochem/physiol Actions:	all−trans−Retinoic acid (ATRA) is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). The bound RAR and RXR act as transcription factors that regulate the growth and differentiation of both normal and malignant cells. Cytochromes P450 (CYPs) catalyze the 4-hydroxylation of ATRA. Retinoic acid primes embryonic stem cells to become neurons.
General description:	This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia .
Other Notes:	Sales restrictions may apply.

Symbol	GHS07
Signal word	Warning
Hazard statements	H302 - H315
Precautionary statements	P264 - P270 - P280 - P301 + P312 - P302 + P352 - P332 + P313
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

mp	180-181 °C (lit.)
UNSPSC	41116107

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