Venlafaxine hydrochloride
USP/1711268 - United States Pharmacopeia (USP) Reference Standard
Synonym: (+/
CAS Number: 99300-78-4
Empirical Formula (Hill Notation): C17H27NO2 · HCl
Molecular Weight: 313.86
MDL Number: MFCD03658865
Linear Formula: C17H27NO2 · HCl
Product Type: Chemical
| API family | venlafaxine |
| application(s) | pharmaceutical (small molecule) |
| format | neat |
| grade | pharmaceutical primary standard |
| InChI | 1S/C17H27NO2.ClH/c1-18(2) |
| InChI key | QYRYFNHXARDNFZ-UHFFFAOYSA |
| manufacturer/tradename | USP |
| SMILES string | Cl[H].COc1ccc(cc1)C(CN(C) |
| Analysis Note: | These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind. |
| Application: | Venlafaxine hydrochloride USP reference standard intended for use in specified quality tests and assays. Also used to prepare standard, system suitability, and standard stock solution for assay, impurity analysis, and performance test according to the given below monographs of United States Pharmacopeia (USP): • Venlafaxine Hydrochloride • Venlafaxine Tablets • Venlafaxine Hydrochloride Extended-Release Capsules • Desvenlafaxine |
| Biochem/physiol Actions: | Venlafaxine is an antidepressant. The mechanism of the antidepresant action of venlafaxine in humans is associated with its potentiation of neurotransmitter activity in the CNS. Venlafaxine is a potent inhibitor of neuronal serotonin and norepinephrine reuptake and weak inhibitor of dopamine reuptake. Venlafaxine has no significant activity for muscarinic, histaminergic, or α-1 adrenergic receptors in vitro. Venlafaxine does not possess MAO inhibitor activity. |
| General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia   . |
| Other Notes: | Sales restrictions may apply. |
| Symbol |  GHS09 |
| Hazard statements | H411 |
| Precautionary statements | P273 - P391 - P501 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 41116107 |