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Astec® CHIROBIOTIC® T Chiral HPLC Column

SUPELCO/12023AST - 5 μm particle size, L × I.D. 15 cm × 4.6 mm

Synonym: Chiral Stationary Phase Column T

Product Type: Equipment/Book
Catalog Number PKG Qty. Price Quantity
45-12023AST 1 ea
 $2560.00
1/EA		 Add To Favorites

 

agency suitable for USP L63
description HPLC column
L × I.D. 15 cm × 4.6 mm
manufacturer/tradename Astec®
material stainless steel column
matrix High-purity silica gel particle platform
  fully porous particle
matrix active group teicoplanin glycopeptide phase
operating pH range 3.8-6.8
packaging pkg of 1 ea
parameter 0-45 °C temperature
  241 bar pressure (3500 psi)
particle size 5 μm
pore size 100 Å
product line Astec®
Quality Level 100 
separation technique chiral
technique(s) HPLC: suitable
  LC/MS: suitable
Application:


  • Chiral liquid chromatography-mass spectrometry (LC-MS/MS) method development for the detection of salbutamol in urine samples.: This study details the application of chiral liquid chromatography coupled with mass spectrometry for detecting salbutamol in urine, highlighting the column′s utility in sensitive biomedical assays ( Chan et al., 2016 ).


  • High-performance liquid chromatographic enantioseparation of 2-aminomono- and dihydroxycyclopentanecarboxylic and 2-aminodihydroxycyclohexanecarboxylic acids on macrocyclic glycopeptide-based phases.: This research demonstrates the column′s effectiveness in enantioseparating specific cyclical amino acids, proving its versatility and importance in chiral separations ( Berkecz et al., 2009 ).
General description: CHIROBIOTIC® T and T2 have teicoplanin as the chiral selector. They offer unique selectivity for a number of classes of molecules, specifically underivatized α, β, γ and cyclic amino acids, N-derivatized amino acids, hydroxy-carboxylic acids, acidic compounds including carboxylic acids and phenols, small peptides, neutral aromatic analytes and cyclic aromatic and aliphatic amines. Separations normally obtained on a chiral crown ether or ligand exchange-type CSPs are also possible on the CHIROBIOTIC® T and T2, but in much simpler mobile phases, like water-alcohol. In addition, all of the known beta-blockers (amino alcohols), and dihydrocoumarins have been resolved. CHIROBIOTIC® T and T2 differ in their bonding chemistry and the pore size of the support particle, giving them different selectivity and preparative capacity.

• Bonded phase: Teicoplanin
• Operating pH range: 3.8 - 6.8
• Particle diameter: 5, 10 or 16 μm
• Pore size: 100 Å (CHIROBIOTIC® T) or 200 Å (CHIROBIOTIC® T2)

CHIROBIOTIC FAQs 
CHIROBIOTIC Reference Bibliography 
Chiral Product Literature 
Legal Information: Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
Legal Information: CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC
Other Notes: Discover LiChropur reagents ideal for HPLC  or LC-MS  analysis
UNSPSC 41115700

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