Astec^® CHIROBIOTIC^® T Chiral HPLC Column

SUPELCO/12023AST - 5 μm particle size, L × I.D. 15 cm × 4.6 mm

Synonym: Chiral Stationary Phase Column T

Product Type: Equipment/Book

Catalog Number	PKG Qty.	Price	Quantity


45-12023AST	1 ea	$2380.00 1/EA		Add To Favorites

Properties
Descriptions
Basic Data

agency	suitable for USP L63
description	HPLC column
L × I.D.	15 cm × 4.6 mm
manufacturer/tradename	Astec^®
material	stainless steel column
matrix	High-purity silica gel particle platform
	fully porous particle
matrix active group	teicoplanin glycopeptide phase
operating pH range	3.8-6.8
packaging	pkg of 1 ea
parameter	0-45 °C temperature
	241 bar pressure (3500 psi)
particle size	5 μm
pore size	100 Å
product line	Astec^®
Quality Level	100
separation technique	chiral
technique(s)	HPLC: suitable
	LC/MS: suitable

Application:	Chiral liquid chromatography-mass spectrometry (LC-MS/MS) method development for the detection of salbutamol in urine samples.: This study details the application of chiral liquid chromatography coupled with mass spectrometry for detecting salbutamol in urine, highlighting the column′s utility in sensitive biomedical assays ( Chan et al., 2016 ). High-performance liquid chromatographic enantioseparation of 2-aminomono- and dihydroxycyclopentanecarboxylic and 2-aminodihydroxycyclohexanecarboxylic acids on macrocyclic glycopeptide-based phases.: This research demonstrates the column′s effectiveness in enantioseparating specific cyclical amino acids, proving its versatility and importance in chiral separations ( Berkecz et al., 2009 ).
General description:	CHIROBIOTIC^® T and T2 have teicoplanin as the chiral selector. They offer unique selectivity for a number of classes of molecules, specifically underivatized α, β, γ and cyclic amino acids, N-derivatized amino acids, hydroxy-carboxylic acids, acidic compounds including carboxylic acids and phenols, small peptides, neutral aromatic analytes and cyclic aromatic and aliphatic amines. Separations normally obtained on a chiral crown ether or ligand exchange-type CSPs are also possible on the CHIROBIOTIC^® T and T2, but in much simpler mobile phases, like water-alcohol. In addition, all of the known beta-blockers (amino alcohols), and dihydrocoumarins have been resolved. CHIROBIOTIC^® T and T2 differ in their bonding chemistry and the pore size of the support particle, giving them different selectivity and preparative capacity. • Bonded phase: Teicoplanin • Operating pH range: 3.8 - 6.8 • Particle diameter: 5, 10 or 16 μm • Pore size: 100 Å (CHIROBIOTIC^® T) or 200 Å (CHIROBIOTIC^® T2) CHIROBIOTIC FAQs CHIROBIOTIC Reference Bibliography Chiral Product Literature
Legal Information:	Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
Legal Information:	CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC
Recommended products:	Discover LiChropur reagents ideal for HPLC or LC-MS analysis

UNSPSC

41115700

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