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Astec® CHIROBIOTIC® R Chiral HPLC Column

SUPELCO/13019AST - 5 μm particle size, L × I.D. 15 cm × 2.1 mm

Synonym: CHIROBIOTIC R Chiral Chromatography Column

Product Type: Equipment/Book
Catalog Number PKG Qty. Price Quantity
45-13019AST 1 ea
 $3650.00
1/EA		 Add To Favorites

 

description HPLC column
L × I.D. 15 cm × 2.1 mm
manufacturer/tradename Astec®
material stainless steel column
matrix high-purity silica gel particle platform
  fully porous particle
matrix active group ristocetin A glycopeptide phase
operating pH range 3.5-6.8
packaging pkg of 1 ea
parameter 0-45 °C temperature
  241 bar pressure (3500 psi)
particle size 5 μm
pore size 100 Å
product line Astec®
Quality Level 100 
separation technique chiral
technique(s) HPLC: suitable
  LC/MS: suitable
Application:

  • Sensitive determination of D-lactic acid and L-lactic acid in urine by high-performance liquid chromatography-tandem mass spectrometry.: This study demonstrates the application of the Astec CHIROBIOTIC R Chiral HPLC Column in the sensitive determination of D-lactic acid and L-lactic acid in urine samples using HPLC-MS/MS. This highlights its utility in clinical and biomedical research for the analysis of chiral molecules in biological fluids (Henry et al., 2012 ).

  • New high-performance liquid chromatography method for the determination of (R)-warfarin and (S)-warfarin using chiral separation on a glycopeptide-based stationary phase.: This research utilizes the Astec CHIROBIOTIC R Chiral HPLC Column to develop a method for the chiral separation and determination of warfarin enantiomers. It underscores the column′s application in pharmaceutical analysis, particularly in the study of chiral drug enantiomers (Malakova et al., 2009 ).
General description: CHIROBIOTIC® R, based on the ristocetin A glycopeptide covalently bonded to high purity silica particles, has shown particular applicability to enantiomers of anionic compounds. Selectivity on CHIROBIOTIC® R strongly correlates to the organic modifier, favoring the alcohol-type mobile phases by a large margin.

• Bonded phase: Ristocetin A
• Operating pH range: 3.5 - 6.8
• Particle diameter: 5, 10 or 16 μm
• Pore size: 100 Å

CHIROBIOTIC FAQs 
CHIROBIOTIC Reference Bibliography 
Chiral Product Literature 
Legal Information: Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
Legal Information: CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC
Recommended products: Discover LiChropur reagents ideal for HPLC  or LC-MS  analysis
UNSPSC 41115700

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