Astec^® CHIROBIOTIC^® V2 Chiral HPLC Column

SUPELCO/15023AST - 5 μm particle size, L × I.D. 15 cm × 4.6 mm

Synonym: CHIROBIOTIC V2 Chiral Chromatography Column

Product Type: Equipment/Book

Catalog Number	PKG Qty.	Price	Quantity


45-15023AST	1 ea	$2380.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

agency	suitable for USP L88
description	HPLC column
L × I.D.	15 cm × 4.6 mm
manufacturer/tradename	Astec^®
material	stainless steel column
matrix	High-purity silica gel particle platform
	fully porous particle
matrix active group	vancomycin phase
operating pH range	3.5-7.0
packaging	pkg of 1 ea
parameter	0-45 °C temperature
	241 bar pressure (3500 psi)
particle size	5 μm
pore size	200 Å
product line	Astec^®
Quality Level	100
separation technique	chiral
technique(s)	HPLC: suitable
	LC/MS: suitable

Application:	Development and validation of an UFLC-MS/MS method for enantioselectivity determination of d,l-thero-methylphenidate, d,l-thero-ethylphenidate and d,l-thero-ritalinic acid in rat plasma and its application to pharmacokinetic study.: This research showcases the Astec^® CHIROBIOTIC^® V2 Chiral HPLC Column′s capacity for precise enantioselective analysis in pharmacokinetic studies, specifically for psychoactive substances. It highlights the column’s effectiveness in separating and quantifying chiral drugs and their metabolites in plasma, providing valuable insights for drug development and therapeutic monitoring (Zhang et al., 2016 ). New high-performance liquid chromatography method for the determination of (R)-warfarin and (S)-warfarin using chiral separation on a glycopeptide-based stationary phase.: This study illustrates the use of the Astec^® CHIROBIOTIC^® V2 Chiral HPLC Column for the chiral separation of warfarin enantiomers. The methodology developed provides a robust tool for the analysis of anticoagulant drugs, aiding in the assessment of their pharmacokinetics and optimizing dosage for therapeutic efficacy (Malakova et al., 2009 ).
General description:	Neutral molecules, amides, acids, esters and amines show considerable enantioselectivity on these vancomycin-based CSPs. A wide variety of secondary and tertiary amines have been separated on the CHIROBIOTIC^® V in the polar ionic mode. The CHIROBIOTIC^® V has demonstrated many of the separation characteristics of protein-based stationary phases, but with exceptional stability and much higher sample capacity. Some chiral analytes have been resolved that have not been reported separated on any other chiral stationary phase. CHIROBIOTIC^® V and V2 differ in their bonding chemistry the pore size of the support particle, giving them different selectivity and preparative capacity. • Bonded phase: Vancomycin • Operating pH range: 3.5 - 7.0 • Particle diameter: 5, 10 or 16 μm • Pore size: 100 Å (CHIROBIOTIC^® V) or 200 Å (CHIROBIOTIC^® V2) CHIROBIOTIC FAQs CHIROBIOTIC Reference Bibliography Chiral Product Literature
Legal Information:	Astec is a registered trademark of Merck KGaA, Darmstadt, Germany
Legal Information:	CHIROBIOTIC is a registered trademark of Sigma-Aldrich Co. LLC
Recommended products:	Discover LiChropur reagents ideal for HPLC or LC-MS analysis

WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

UNSPSC

41115700

Choose a favorite list for this item:

Catalog Number	Description	Price

		$

Please choose a list :

Continue Shopping

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.