LiChrospher^® RP-18 HPLC Column

SUPELCO/50139-U - 5 μm particle size, L × I.D. 25 cm × 4.6 mm, endcapped

Synonym: TM=["LiChrospher"] C18 HPLC column

Product Type: Equipment/Book

Catalog Number	PKG Qty.	Price


45-50139-U	1 ea	$973.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

agency	suitable for USP L1
application(s)	food and beverages
extent of labeling	21% Carbon loading
feature	endcapped
L × I.D.	25 cm × 4.6 mm
manufacturer/tradename	LiChrospher^®
material	stainless steel column
matrix	octadecyl
	silica particle platform
	fully porous particle
matrix active group	C18 (octadecyl) phase
operating pH	2-7.5
packaging	1 ea of
parameter	≤65 °C temperature
	≤70 °C temp. range
	400 bar pressure (5801 psi)
particle size	5 μm
pore size	100 Å
product line	LiChrospher^®
Quality Level	100
separation technique	reversed phase
surface area	350 m²/g
technique(s)	HPLC: suitable

Application:	HPLC-UV and GC-MS Methods for Determination of Chlorambucil and Valproic Acid in Plasma for Further Exploring a New Combined Therapy of Chronic Lymphocytic Leukemia.: This study illustrates the efficiency of the LiChrospher^® RP-18 HPLC Column in a novel approach to analyzing the pharmacokinetics of chlorambucil and valproic acid, providing critical data for potential combined therapy options in treating chronic lymphocytic leukemia (Lipska et al., 2021 ). Rapid Determination of Metronidazole and 2-Hydroxymetronidazole in Murine Blood Plasma.: Utilizes the LiChrospher^® RP-18 HPLC Column to establish a rapid and accurate method for the analysis of metronidazole and its metabolites in blood plasma, enhancing the understanding of its pharmacological impacts and supporting more effective therapeutic strategies (Zemanova et al., 2022 ). Application of chemometric approach for development and validation of high performance liquid chromatography method for estimation of ropinirole hydrochloride.: Demonstrates the application of the LiChrospher^® RP-18 HPLC Column in optimizing a chemometrically enhanced method for the determination of ropinirole hydrochloride, aimed at improving treatment strategies for Parkinsons disease (Fatima et al., 2019 ). Application of an HPLC-MS/MS method for Teicoplanin drug substance and related impurities, part 2: Identity assignment of related impurities.: This research highlights the capability of the LiChrospher^® RP-18 HPLC Column in detailed impurity profiling of teicoplanin, critical for maintaining drug purity and efficacy in antibiotic treatments (Tengattini et al., 2019 ).
General description:	LiChrosorb^® RP-18 HPLC Column are classified as L1 USP columns and primarily used for reversed-phase HPLC of neutral, acidic and weak basic compounds. The totally porous irregular particles ensure reliable results.
General description:	LiChrospher^® RP-18 HPLC column is an incredibly reliable and highly versatile, traditionally manufactured spherical silica-based support, designed for reversed-phase chromatography of acidic, neutral and weakly basic compounds - substances frequently found in all analytical fields. The optimal selectivity and performance of the column ensure that these parameters remain constant from batch to batch and from year to year.
Legal Information:	LiChrosorb is a registered trademark of Merck KGaA, Darmstadt, Germany
Legal Information:	LiChrospher is a registered trademark of Merck KGaA, Darmstadt, Germany
Recommended products:	Discover LiChropur reagents ideal for HPLC or LC-MS analysis

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

UNSPSC

41115700

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