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Nucleosil® C18 HPLC Column

SUPELCO/50165-U - 5 μm particle size, L × I.D. 12.5 cm × 4 mm

Synonym: C18 reversed-phase HPLC column

Product Type: Equipment/Book
Catalog Number PKG Qty. Price Quantity
45-50165-U 1 ea
 $764.00
1/EA		 Add To Favorites
agency suitable for USP L1
extent of labeling 15% Carbon loading
feature endcapped
L × I.D. 12.5 cm × 4 mm
manufacturer/tradename Nucleosil®
matrix octadecyl
matrix active group C18 (octadecyl) phase
parameter ≤70 °C temp. range
  400 bar pressure (5801 psi)
particle size 5 μm
pore size 100 Å
product line Nucleosil®
Quality Level 100 
separation technique reversed phase
surface area 350 m2/g
technique(s) HPLC: suitable
Application:

  • Quantification and Validation of Stability-Indicating RP-HPLC Method for Efavirenz: Demonstrates the utility of Nucleosil® C18 HPLC Column in pharmaceutical analysis, particularly in quality control and stability testing of Efavirenz, ensuring compliance with regulatory standards (Gurumukhi VC, Bari SB, 2022 ).

  • Development of new method for simultaneous analysis of piracetam and levetiracetam: This study uses the Nucleosil® C18 column to develop robust methods for analyzing neurological medications in pharmaceuticals and biological fluids, contributing to drug stability studies (Siddiqui FA et al., 2014 ).

  • HPLC method for determination of biologically active epoxy-transformers of treosulfan: The column′s application in plasma analysis highlights its role in pharmacokinetic studies, offering precise measurements critical for dosing and therapeutic monitoring (Główka FK et al., 2012 ).

  • HPLC analysis of mitoxantrone in mouse plasma and tissues: Illustrates the column′s effectiveness in a pharmacokinetic study, underscoring its importance in the preclinical evaluation of cancer therapies (An G, Morris ME, 2010 ).

  • Development and validation of an HPLC method for vancomycin: This application in a pharmacokinetic study highlights the column′s critical role in the development and validation of methods for antibiotic analysis, ensuring therapeutic efficacy and safety (Jesús Valle MJ et al., 2008 ).
Legal Information: Nucleosil is a registered trademark of Macherey-Nagel GmbH & Co. KG
Recommended products: Discover LiChropur reagents ideal for HPLC  or LC-MS  analysis
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
UNSPSC 41115700

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