Ascentis^® Express F5, 2.7 μm HPLC Column

SUPELCO/53577-U - 2.7 μm particle size, L × I.D. 7.5 cm × 3 mm

Synonym: Core-shell (SPP) Fused Core PFP HPLC column

Product Type: Equipment/Book

Catalog Number	PKG Qty.	Price


45-53577-U	1 ea	$821.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

agency	suitable for USP L43
application(s)	food and beverages
feature	endcapped
impurities	<5 ppm metals
L × I.D.	7.5 cm × 3 mm
manufacturer/tradename	Ascentis^®
material	stainless steel column
matrix	Fused-Core particle platform
	superficially porous particle
matrix active group	PFP (pentafluorophenyl) phase
operating pH	2-8
packaging	1 ea of
parameter	60 °C temp. range
	600 bar max. pressure (9000 psi)
particle size	2.7 μm
pore size	90 Å pore size
product line	Ascentis^®
Quality Level	100
separation technique	reversed phase
surface area	135 m²/g
technique(s)	HPLC: suitable
	LC/MS: suitable
	UHPLC-MS: suitable
	UHPLC: suitable

Application:	Liquid chromatographic determination of lumacaftor in the presence of ivacaftor and identification of five novel degradation products using high-performance liquid chromatography ion trap time-of-flight mass spectrometry.: This study utilizes the Ascentis^® Express F5, 2.7 µm HPLC Column to develop a robust method for the determination of lumacaftor in the presence of ivacaftor, identifying five novel degradation products. The high resolution and efficiency of the column were crucial for the detailed analysis and identification process. (Özcan et al., 2023 ). Stability-indicating LC-MS/MS and LC-DAD methods for robust determination of tasimelteon and high resolution mass spectrometric identification of a novel degradation product.: The Ascentis^® Express F5 column was employed to develop stability-indicating methods for tasimelteon, ensuring accurate determination and high-resolution identification of degradation products, highlighting the column′s effectiveness in stability studies and complex sample matrices. (Özcan et al., 2020 ). Recent trends in ultra-fast HPLC: new generation superficially porous silica columns.: This review discusses advancements in ultra-fast HPLC, focusing on new generation superficially porous silica columns like the Ascentis^® Express F5. The article elaborates on the performance improvements and applications in analytical chemistry, emphasizing the column′s role in enhancing speed and resolution. (Ali et al., 2012 ).
General description:	The pentafluorophenylpropyl stationary phase of Ascentis Express F5 provides a stable reversed phase packing with electron-deficient phenyl rings due to the presence of electronegative fluorines.In addition to forming pi-pi and mildly steric interactions, F5 phases also retain compounds by polar interactions. Ascentis Express F5 can be used for basic, acidic, or neutral compounds with alternate selectivity from C18.
Legal Information:	Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

UNSPSC

41115700

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