Discovery^® C18 HPLC Column

SUPELCO/569232-U - 5 μm particle size, L × I.D. 12.5 cm × 4.6 mm

Synonym: Discovery RP18 HPLC Column

Product Type: Equipment/Book

Catalog Number	PKG Qty.	Price


45-569232-U	1 ea	$828.00 1/EA	Add To Favorites

Properties
Descriptions
Basic Data

agency	suitable for USP L1
application(s)	food and beverages
extent of labeling	12% Carbon loading
feature	endcapped
impurities	<10 ppm metals
L × I.D.	12.5 cm × 4.6 mm
manufacturer/tradename	Discovery^®
material	stainless steel column
matrix	silica gel, high purity, spherical particle platform
	fully porous particle
matrix active group	C18 (octadecyl) phase
operating pH range	2-8
packaging	1 ea of
parameter	≤70 °C temp. range
	400 bar pressure (5801 psi)
particle size	5 μm
pore size	180 Å
product line	Discovery^®
Quality Level	100
separation technique	reversed phase
surface area	300 m²/g
surface coverage	3 μmol/m²
technique(s)	HPLC: suitable
	LC/MS: suitable

Application:	Rat Pharmacokinetics and In Vitro Metabolite Identification of KM-819, a Parkinson′s Disease Candidate, Using LC-MS/MS and LC-HRMS.: This study underscores the utility of theDiscovery^® C18 HPLC Column in pharmacokinetic profiling and metabolite identification of a novel therapeutic agent, demonstrating its critical role in the development of Parkinson′s disease treatments (Choi et al., 2024 ). Determination of 2,4-dimethylhydroxybenzene by chromatographic methods in forensic toxicological research of biological material.: Highlights the application of the Discovery^® C18 HPLC Column in forensic toxicology, enhancing the detection and quantification of toxic substances within biological samples, vital for legal and medical investigations (Chernova et al., 2024 ). High-throughput microfluidic chip with silica gel-C18 channels for cyclotide separation.: Illustrates the integration of the Discovery^® C18 HPLC Column in a microfluidic setting for efficient and high-throughput separation of cyclotides, offering advancements in peptide and protein analysis (Ebrahimi et al., 2023 ). Priestia megaterium Metabolism: Isolation, Identification of Naringenin Analogues and Genes Elevated Associated with Nanoparticle Intervention.: This research utilizes the Discovery^® C18 HPLC Column for the advanced study of microbial metabolism under nanoparticle intervention, pushing the boundaries of biotechnological and pharmaceutical research (Al-Theyab et al., 2023 ). A practical strategy enabling more reliable identification of ginsenosides from Panax quinquefolius flower by dimension-enhanced liquid chromatography/mass spectrometry and quantitative structure-retention relationship-based retention behavior prediction.: Demonstrates the versatility of the Discovery^® C18 HPLC Column in complex botanical analyses, particularly in enhancing the reliability of ginsenoside identification, crucial for the development of herbal medicinal products (Sun et al., 2023 ).
Features and Benefits:	• Excellent reproducibility • Exceptional peak shape for basic and acidic analytes • Stable, low-bleed LC-MS separations • Separation of peptides and small proteins • Lower hydrophobicity than many comparable C18 columns, providing faster analysis
General description:	Use Discovery® C18 for any method that specifies a C18. The exceptional peak shape, reproducibility, and stability make it the column of choice for all C18 methods from demanding to routine.
Legal Information:	Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany
Recommended products:	Discover LiChropur reagents ideal for HPLC or LC-MS analysis

UNSPSC

41115700

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