Discovery^® HS C18 HPLC Column

SUPELCO/569252-U - 3 μm particle size, L × I.D. 15 cm × 4.6 mm

Synonym: Discovery RP18 HPLC Column

Product Type: Equipment/Book

Catalog Number	PKG Qty.	Price


45-569252-U	1 ea	$1090.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

agency	suitable for USP L1
application(s)	food and beverages
extent of labeling	20% Carbon loading
feature	endcapped
impurities	<10 ppm metals
L × I.D.	15 cm × 4.6 mm
manufacturer/tradename	Discovery^®
material	stainless steel column
matrix	silica gel, high purity, spherical particle platform
	fully porous particle
matrix active group	C18 (octadecyl) phase
operating pH range	2-8
packaging	1 ea of
parameter	≤70 °C temp. range
	400 bar pressure (5801 psi)
particle size	3 μm
pore size	120 Å
product line	Discovery^®
Quality Level	100
separation technique	reversed phase
surface area	300 m²/g
surface coverage	3.2 μmol/m²
technique(s)	HPLC: suitable
	LC/MS: suitable

Application:	A stability indicating RP-HPLC method for determination of the COVID-19 drug molnupiravir applied using nanoformulations in permeability studies.: This research developed a robust RP-HPLC method for the quantitative analysis of molnupiravir, a COVID-19 therapeutic, utilizing nanoformulations. The study highlights the method′s stability and effectiveness in permeability studies, demonstrating its potential in pharmaceutical analysis (Reçber et al., 2022 ). Analysis of terizidone in plasma using HPLC-UV method and its application in a pharmacokinetic study of patients with drug-resistant tuberculosis.: The study developed and validated an HPLC-UV method for analyzing terizidone in plasma, essential for pharmacokinetic studies in patients with drug-resistant tuberculosis. The method′s reliability supports its use in clinical and pharmacological research (Mulubwa and Mugabo, 2018 ). Optimization of LC method for the quantification of doxorubicin in plasma and urine samples in view of pharmacokinetic, biomedical and drug monitoring therapy studies.: This research focuses on optimizing a liquid chromatography method to quantify doxorubicin in plasma and urine. It is crucial for pharmacokinetic, biomedical, and drug monitoring studies, ensuring accurate and precise therapeutic monitoring (Maliszewska et al., 2018 ). Universal efavirenz determination in transport study, rat placenta perfusion and placenta lysate by HPLC-UV.: This study introduces a universal HPLC-UV method for determining efavirenz in various biological matrices, including transport studies, rat placenta perfusion, and lysate. It is significant for pharmacokinetic and drug distribution research (Zelena et al., 2017 ).
Features and Benefits:	• Stable, low bleed for LC-MS applications • Scalable from analytical to preparatory • Highly stable to ensure excellent run-to-run and lot-to-lot reproducibility • Higher hydrophobicity for better resolution of difficult analytes
Legal Information:	Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany
Recommended products:	Discover LiChropur reagents ideal for HPLC or LC-MS analysis

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

UNSPSC

41115700

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