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SUPELCOSIL™ LC-CN HPLC Column

SUPELCO/58221-U - 5 μm particle size, L × I.D. 15 cm × 4.6 mm

Synonym: MTO-SUPELCOSIL™ LC-CN 5UM 15CMX4.6MM HPLC COLUMN

Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-58221-U 1 ea
 $0.00
1/EA
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agency suitable for USP L10
extent of labeling 4% Carbon loading
feature endcapped
L × I.D. 15 cm × 4.6 mm
material stainless steel column
matrix silica gel, spherical particle platform
  fully porous particle
matrix active group cyano phase
packaging 1 ea of
parameter ≤70 °C temp. range
particle size 5 μm
pH range 2-7.5
pore size 120 Å
product line SUPELCOSIL™
Quality Level 100 
separation technique hydrophilic interaction (HILIC)
  normal phase
  reversed phase
surface area 170 m2/g
surface coverage surface coverage 3.5 μmol/m2
technique(s) HPLC: suitable
Application:

  • Validated Simple HPLC-UV Method for Mycophenolic Acid (MPA) Monitoring in Human Plasma. Internal Standardization: : This study presents a validated HPLC-UV method for monitoring mycophenolic acid in human plasma. The research highlights the necessity and efficiency of internal standardization in achieving accurate measurements. (Kunicki PK et al., 2021 ).

  • An Improved HPLC Method for Therapeutic Drug Monitoring of Daunorubicin, Idarubicin, Doxorubicin, Epirubicin, and Their 13-dihydro Metabolites in Human Plasma.: This paper describes an enhanced HPLC method for monitoring therapeutic levels of several chemotherapeutic agents and their metabolites in human plasma, improving the accuracy and reliability of drug monitoring. (Fogli S et al., 1999 ).

  • Analysis of Diltiazem and Desacetyldiltiazem in Serum by High-Performance Liquid Chromatography.: This research focuses on an HPLC method for analyzing diltiazem and its primary metabolite in serum, providing a robust tool for clinical pharmacokinetic studies. (Paczkowski D et al., 1995 ).

  • High-Performance Liquid Chromatographic Method for the Determination of Eclanamine and Its N-Desmethyl and N,N-Didesmethyl Metabolites in Urine.: The study details a high-performance liquid chromatographic method for determining eclanamine and its metabolites in urine, crucial for pharmacokinetic and toxicological analysis. (Lakings DB et al., 1988 ).
General description: The LC-CN phase is often used as a substitute for silica because it offers the advantages of a bonded phase (such as quick equilibration, and less sensitivity to small changes of the water content in the mobile phase). More often, however, the LC-CN column is operated under reversed-phase mobile phase conditions.
Legal Information: SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
Recommended products: Discover LiChropur reagents ideal for HPLC  or LC-MS  analysis
UNSPSC 41115700

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