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SUPELCOSIL LC-CN HPLC Column

SUPELCO/58979C30 - 3 μm particle size, L × I.D. 3.3 cm × 3 mm

Synonym: Cyanopropyl HPLC Column

Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-58979C30 1 ea
$558.00
1/EA
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agency suitable for USP L10
application(s) food and beverages
extent of labeling 4% Carbon loading
feature endcapped
L × I.D. 3.3 cm × 3 mm
manufacturer/tradename SUPELCOSIL
material stainless steel column
matrix silica gel, spherical particle platform
  fully porous particle
matrix active group cyano phase
packaging 1 ea of
parameter ≤70 °C temp. range
  400 bar pressure (5801 psi)
particle size 3 μm
pH range 2-7.5
pore size 120 Å
product line SUPELCOSIL
Quality Level 100 
separation technique hydrophilic interaction (HILIC)
  normal phase
  reversed phase
surface area 170 m2/g
surface coverage surface coverage 3.5 μmol/m2
technique(s) HPLC: suitable
Application:

  • Validated Simple HPLC-UV Method for Mycophenolic Acid (MPA) Monitoring in Human Plasma. Internal Standardization: : This study presents a validated HPLC-UV method for monitoring Mycophenolic Acid in human plasma, emphasizing the role of internal standardization in accuracy and precision of the results. The SUPELCOSIL LC-CN HPLC column was utilized for its effective separation capabilities (Kunicki and Wróbel, 2021 ).

  • An Improved HPLC Method for Therapeutic Drug Monitoring of Daunorubicin, Idarubicin, Doxorubicin, Epirubicin, and Their 13-Dihydro Metabolites in Human Plasma: This paper details an enhanced HPLC method for monitoring various anthracycline drugs in human plasma. The use of the SUPELCOSIL LC-CN HPLC column improved the detection and quantification of these drugs and their metabolites (Fogli et al., 1999 ).

  • Analysis of Diltiazem and Desacetyldiltiazem in Serum by High-Performance Liquid Chromatography: This research focused on developing a precise HPLC method to analyze diltiazem and its metabolite in serum, employing the SUPELCOSIL LC-CN HPLC column for effective separation and detection (Paczkowski et al., 1995 ).

  • High-Performance Liquid Chromatographic Method for the Determination of Eclanamine and Its N-Desmethyl and N,N-Didesmethyl Metabolites in Urine: This study describes a robust HPLC method for determining eclanamine and its metabolites in urine, utilizing the SUPELCOSIL LC-CN HPLC column for its high-resolution capabilities (Lakings et al., 1988 ).

General description: The LC-CN phase is often used as a substitute for silica because it offers the advantages of a bonded phase (such as quick equilibration, and less sensitivity to small changes of the water content in the mobile phase). More often, however, the LC-CN column is operated under reversed-phase mobile phase conditions.
Legal Information: SUPELCOSIL is a trademark of Sigma-Aldrich Co. LLC
Recommended products: Discover LiChropur reagents ideal for HPLC  or LC-MS  analysis
UNSPSC 41115700

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