Discovery® Cyano HPLC Column
SUPELCO/59356-U - 5 μm particle size, L × I.D. 15 cm × 4.6 mm
Synonym: Cyano Bonded Phase Column
Product Type: Equipment/Book
| agency | suitable for USP L10 |
| application(s) | food and beverages |
| extent of labeling | 4.5% Carbon loading |
| feature | endcapped |
| impurities | <10 ppm metals |
| L × I.D. | 15 cm × 4.6 mm |
| manufacturer/tradename | Discovery® |
| material | stainless steel column |
| matrix | silica gel, high purity, spherical base material |
| fully porous particle | |
| matrix active group | cyano phase |
| operating pH range | 2-8 |
| packaging | 1 ea of |
| parameter | ≤70 °C temp. range |
| 400 bar pressure (5801 psi) | |
| particle size | 5 μm |
| pore size | 180 Å |
| product line | Discovery® |
| Quality Level | 100 ![]() |
| separation technique | hydrophilic interaction (HILIC) |
| normal phase | |
| reversed phase | |
| surface area | 200 m2/g |
| surface coverage | 3.5 μmol/m2 |
| technique(s) | HPLC: suitable |
| LC/MS: suitable |
| Application: | Discovery Cyano HPLC columns provide a lower hydrophobicity than C18 or C8 and different selectivity. Typical applications are the separation of Flavonoids, Phenols, Phthalates, Steroids, Sulfonamides, Oils and Alcohols. |
| Features and Benefits: | • Low hydrophobicity for rapid elution of hydrophobic analytes • Excellent peak shape and retention of strongly basic analytes • Retention of polar analytes • Unique selectivity • Significantly less retention than C18 (typically requires lower % organic mobile phase) • Stable, low-bleed LC-MS separations • Compatible with highly aqueous organic phases |
| General description: | Discovery® Cyano HPLC column is used for the retention and separation of strongly basic analytes including quaternary ammonium salts, with excellent peak shapes. |
| Legal Information: | Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 41115700 |

